Yes, Zenegra 50 mg, which contains sildenafil (the same active ingredient as Viagra and Kamagra), can cause digestive issues as a potential side effect. Some common gastrointestinal side effects associated with sildenafil-based medications like Zenegra include:

Indigestion (Dyspepsia): This is one of the more common digestive issues, characterized by discomfort or a feeling of fullness in the upper abdomen.

Heartburn: Some individuals may experience acid reflux or a burning sensation in the chest, which is commonly known as heartburn.

Nausea: In some cases, people may feel nauseous after taking Zenegra 50 mg.

Diarrhea: Though less common, diarrhea can occur as a side effect of sildenafil.

These side effects are usually mild and temporary. However, if you experience severe or persistent digestive issues, it’s important to consult your healthcare provider. They may adjust your dosage or recommend a different treatment for erectile dysfunction if the side effects are bothersome.

To minimize the likelihood of digestive issues, it’s generally advised to take the medication on an empty stomach, as high-fat meals can sometimes increase the risk of gastrointestinal discomfort when using sildenafil-based drugs.